Vibrotactile Coordinated Reset for the Treatment of Chronic Stroke

Inclusion Criteria:

1. Age at the time of enrollment: 18-80 years

2. Diagnosis of ischemic or hemorrhagic stroke

3. Disease period of more than 6 months

4. Mini Mental State Examination of at least 24 points

5. No medications that affect balance

6. Motor deficit

7. Use of Motricity Arm and Leg index to include impaired individuals with somefunctioning

8. Modified Rankin Scale for Neurologic Disability: Scores 3 or 4

Exclusion Criteria:

1. Any significant psychiatric problems, including acute confusional state (delirium),ongoing psychosis, or clinically significant depression

2. Any current drug or alcohol abuse

3. History of recurrent or unprovoked seizures

4. Any neurological disorder treatments that involve intracranial surgery or deviceimplantation

5. Participation in another drug, device or biologic trial concurrently or within thepreceding days

6. Pregnancy, breastfeeding or wanting to become pregnant during the trial

7. History or presence of other major neurological or orthopedic diseases other thanstroke that limits motor functioning or cognitive ability

8. More than 5 degrees of contracture at shoulder, elbow, wrist, finger, hip, knee, orankle

9. Botox, baclofen or any other treatment for spasticity except for bracing orsplinting within the previous 3 months

10. Must be able to communicate with staff

11. Severe sensory abnormalities of the fingers such as vibratory urticaria