TCA 15% Chemical Peel for Improvement in Hand Lentigines

Last updated: March 14, 2025
Sponsor: Main Line Center for Laser Surgery
Overall Status: Completed

Phase

4

Condition

Skin Aging

Treatment

15% Trichloroacetic acid + 3% glycolic acid

Clinical Study ID

NCT05471947
SC20220721
  • Ages > 22
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age >21

  • No laser, chemical peel, neuromodulator, filler treatment to the hands in >3 months

  • At least 5 lentigines on each hand

Exclusion

Exclusion Criteria:

  • Pregnancy

  • Breastfeeding

  • Allergy to trichloroacetic acid

  • Allergy to glycolic acid

  • Open wounds on treatment area (hands)

  • Active inflammatory disease on treatment area such as atopic dermatitis, psoriasis,dermatomyositis

Study Design

Total Participants: 20
Treatment Group(s): 1
Primary Treatment: 15% Trichloroacetic acid + 3% glycolic acid
Phase: 4
Study Start date:
March 15, 2023
Estimated Completion Date:
December 01, 2024

Study Description

This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.

A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.

Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.

Four to six weeks after their final treatment, subjects will return for photography.

Connect with a study center

  • Main Line Center for Laser Surgery

    Ardmore, Pennsylvania 19003
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.