Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.

Inclusion Criteria:

• Aged 18-75 years old;
• Adjuvant hormone therapy (eg, tamoxifen and/or aromatase inhibitors) with or withoutovarian function suppression has been administered for at least 4 weeks and iscurrently on treatment;
• Vasomotor syndrome for at least 6 weeks;
• Premenopausal or postmenopausal patients;
• Patients with persistent hot flashes for at least 4 weeks and with a frequency of morethan 14 hot flashes per week (2 times per day) in the week before inclusion in thestudy, the weekly average hot flash composite score is 3-4;
• Patients after surgery and after chemotherapy (if any);
• Eastern Cooperative Oncology Group score of 0-1 points.
• Sign the informed consent and voluntarily participate in this clinical observation.

Exclusion Criteria:

• Tumor metastases, undergoing chemoradiotherapy or planning surgery;
• Pharmacological intervention for hot flashes with hot flash treatment drugs such asselective serotonin reuptake inhibitors (SSRIs) and/or anticonvulsants for at least 4weeks prior to study initiation;
• Unstable heart disease or myocardial infarction within 6 months prior to study start;
• Started or changed adjuvant hormone therapy within the past week, or who planned tostart or change adjuvant hormone therapy in the past 14 weeks;
• Seizures of unknown likelihood or history of seizures;
• Have used acupuncture for hot flashes within 6 months prior to the start of the study;
• Pregnant or breastfeeding patients;
• Apparent uncontrolled infection;
• Mental illness or family history; neurological disorder or family history.