A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients

Last updated: January 31, 2023
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05449470
2021_061
  • Ages > 65
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls. Research indicates fall-risk increasing drug (FRID) deprescribing is effective in reducing falls but difficult to initiate and to sustain over longer periods of follow-up. A clinical decision support system (CDSS) and patient portal for communicating medication-related fall risk to fall clinic patients may improve joint medication management between patients and physicians and consequently reduce the incidence of injurious falls.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • History of at least one fall in the past year;
  • A Mini-Mental State Examination (MMSE) score of 21 points or higher or equivalently aMontreal Cognitive Assessment (MOCA) Dutch score of 16 points or higher;
  • Use of at least one fall-risk increasing drug (FRID); and
  • Sufficient command of the Dutch language in speech and writing.

Exclusion

Exclusion Criteria:

  • Active participation in another study;
  • Life expectancy of less than one year: and/or
  • Suffering from severe mobility impairment (i.e. bedridden, e.g. inability to walkshort distances with assistance of a walking aid).

Study Design

Total Participants: 800
Study Start date:
July 07, 2022
Estimated Completion Date:
June 30, 2024

Study Description

This study investigates the effectiveness and cost-effectiveness of the concurrent use of a CDSS and a patient portal for personalized FRID deprescribing, and will be assessed through a multicenter cluster-randomized controlled trial among new fall clinic patients, aged 65 years or older. The main study parameter is the time to first injurious fall. The primary objective of the ADFICE_IT study is to investigate the effects of a CDSS and accompanying patient portal for optimizing FRID deprescribing on injurious falls. This study has three secondary objectives. First, the effect of the CDSS and patient portal on a number of secondary outcomes will be investigated. Second, a process evaluation to evaluate the implementation of the CDSS and patient portal will be conducted. Third, the cost-effectiveness of the CDSS and patient portal will be investigated.

Connect with a study center

  • Medisch Centrum Leeuwarden

    Leeuwarden, Friesland 8934 AD
    Netherlands

    Site Not Available

  • Radboud universitair medisch centrum

    Nijmegen, Gelderland 6525 GA
    Netherlands

    Site Not Available

  • Elisabeth-TweeSteden Ziekenhuis

    Tilburg, Noord-Brabant 5042 AD
    Netherlands

    Active - Recruiting

  • Ziekenhuis Amstelland

    Amstelveen, Noord-Holland 1186 AM
    Netherlands

    Site Not Available

  • Amsterdam UMC, locatie AMC

    Amsterdam, Noord-Holland 1105 AZ
    Netherlands

    Active - Recruiting

  • Amsterdam UMC, locatie VUmc

    Amsterdam, Noord-Holland 1081 HV
    Netherlands

    Active - Recruiting

  • OLVG

    Amsterdam, Noord-Holland 1091 AC
    Netherlands

    Site Not Available

  • Spaarne Gasthuis

    Haarlem, Noord-Holland 2035 RC
    Netherlands

    Site Not Available

  • UMC Groningen

    Groningen, 9713 GZ
    Netherlands

    Site Not Available

  • St. Antonius Ziekenhuis

    Utrecht, 3543 AZ
    Netherlands

    Site Not Available

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