Sex Differences in E-cig Perception: Study 1

Phase

N/A

Condition

Tobacco Use Disorder

Substance Abuse

Addictions

Treatment

E-liquid Flavor 2

E-liquid Flavor 1

E-liquid Flavor 3

Clinical Study ID

NCT05432830

2000032981

1K01DA056494-01

Ages 21-44
All Genders
Accepts Healthy Volunteers

Study Summary

The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.

Eligibility Criteria

Inclusion

Inclusion Criteria:

21-44 years old
Able to read/write
Current cigarette smoking
Recent E-cig Exposure (>/= 10 uses in past 6 mo.)
Urine cot >200ng/ml
Willing to abstain from nicotine/tobacco 6-8hrs prior to lab session
Not looking to quit

Exclusion

Exclusion Criteria:

Untreated chronic medical conditions
Non-stable Rx medication
Illicit drug use
Pregnant, trying to become pregnant, breastfeeding
Not fully vaccinated for Coronavirus (e.g. COVID-19)

Study Design

E-liquid Flavor 2

April 30, 2024

July 18, 2025

Study Description

This study looks at the effect of sex on the sensory effects of flavor components in e-cigarettes. Regular combustible tobacco users will sample 3 different flavored e-cigarettes containing nicotine in a human lab paradigm.

Connect with a study center

Connecticut Mental Health Center
New Haven, Connecticut 06519
United States
Site Not Available
Connecticut Mental Health Center
New Haven 4839366, Connecticut 4831725 06519
United States
Site Not Available

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