Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

Last updated: July 2, 2025
Sponsor: Memorial Sloan Kettering Cancer Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Non-small Cell Lung Cancer

Treatment

N/A

Clinical Study ID

NCT05424029
22-155
  • Ages > 18
  • All Genders

Study Summary

The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • All patients ≥ 18 years of age undergoing consideration of surgical resection,including lobar resections, sublobar resections, and pneumonectomies, for primarylung cancer will be eligible.

  • Patients with previously resected disease and/or previous radiation therapy will beconsidered on a case by case basis.

Exclusion

Exclusion Criteria:

  • Patients with active infection or pneumonia which may impact exosome makeup

  • Additionally, if at the discretion of the operating surgeon, obtaining bronchialwashings would lead to undue morbidity, the patient would be excluded and replaced

Study Design

Total Participants: 200
Study Start date:
June 14, 2022
Estimated Completion Date:
June 30, 2026

Connect with a study center

  • Memorial Sloan Kettering Basking Ridge (Consent Only)

    Basking Ridge, New Jersey 07920
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Monmouth (Consent Only)

    Middletown, New Jersey 07748
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Bergen (Consent Only)

    Montvale, New Jersey 07645
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Suffolk - Commack (Consent Only)

    Commack, New York 11725
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Westchester (Consent Only)

    Harrison, New York 10604
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center

    New York, New York 10065
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Nassau (Consent Only)

    Uniondale, New York 11553
    United States

    Active - Recruiting

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