Vitamin B12 and Dextrose for Median Nerve Hydrodissection

Last updated: March 20, 2024
Sponsor: National Cheng-Kung University Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Carpal Tunnel Syndrome

Treatment

Ultrasound-guided nerve hydrodissection

Clinical Study ID

NCT05423028
NCKUH-11103036
  • Ages 20-80
  • All Genders

Study Summary

Carpal tunnel syndrome is the most common peripheral entrapment neuropathy of the upper limb. Previous experiments found that ultrasound-guided median nerve hydrodissection with 5% dextrose water could ameliorate the condition of carpal tunnel syndrome. Oral administration of vitamin B 12 had been reported to reduce the discomfort from peripheral neuropathy although the level of evidence is not strong. This prospective, double-blind randomized control trial aims to compare the effects of different kinds of the injection agents on carpal tunnel syndrome.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age between 20-80 year-old.
  • Diagnosis (carpal tunnel syndrome) was confirmed using an electrophysiological study.

Exclusion

Exclusion Criteria:

  • Previously undergone wrist surgery or steroid injection for CTS
  • Thrombocytopenia
  • Coagulopathy
  • Inflammation status
  • Polyneuropathy
  • Brachial plexopathy
  • Cervical radiculopathy
  • Autoimmune disease
  • Malignancy
  • Pregnancy Thoracic outlet syndrome

Study Design

Total Participants: 120
Treatment Group(s): 1
Primary Treatment: Ultrasound-guided nerve hydrodissection
Phase:
Study Start date:
December 07, 2021
Estimated Completion Date:
December 31, 2024

Connect with a study center

  • Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University

    Tainan,
    Taiwan

    Active - Recruiting

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