The Purpose of This Study is to Determine the Frequency of Colorectal Cancer in Male and Female Endurance Athletes Between the Ages of 35 and 50

Inclusion Criteria:

• Adult males and females 35-50 years of age

• Male and female self-reported endurance athletes, defined by at least one of thefollowing:

• Run at least two races of 50 miles or more

• Run 5 races of 26.2 miles or more

• Ability to complete testing in the protocol and make study visits

• Able and willing to consent to protocol

Exclusion Criteria:

• Known or suspected history of inflammatory bowel disease, familial adenomatouspolyposis (FAP), or Lynch Syndrome

• Concomitant illness that would prevent adequate patient assessment or in theinvestigators' opinion pose an added risk for study participants.

• Anticipated poor compliance

• Prisoners or subjects who are involuntarily incarcerated

• Persons with decisional incapacity/cognitive impairment

• Any history or evidence of severe illness or any other condition that would make thepatient, in the opinion of the investigator unsuitable for the study

• Subject is involved with a worker's compensation, personal injury, or other legalmatters related to their health

• Subject is enrolled in a separate interventional clinical trial