Effects of High-intensity Interval Training and Aerobic Exercise on Obstructive Sleep Apnea.

Phase

N/A

Condition

Sleep Apnea Syndromes

Pain (Pediatric)

Treatment

N/A

Clinical Study ID

NCT05416398

2022/57

Ages 18-55
All Genders

Study Summary

Introduction: Obstructive sleep apnea syndrome (OSAS) is a condition characterized by recurrent episodes of partial or complete obstruction of the upper airway (URI) during sleep.

Objective: It was designed to compare the effects of aerobic and high-intensity interval training training on exercise capacity, fatigue, cognitive status, physical and disease-specific parameters in individuals with obstructive sleep apnea syndrome.

Materials and Methods: It was designed as a randomized controlled experimental model. Patients between the ages of 18-55 who were diagnosed with OSAS by polysomnography by a specialist physician, and those with moderate (AHI: 16-30) and severe (AHI> 30) OSAS will be included. After the patients were selected from the relevant population with the improbable random sampling method, the patients who accepted to participate in the study and met the inclusion criteria will be assigned to one of the aerobic exercise group, high-intensity interval training training group or control group with the closed-envelope method. Evaluations will be evaluated for each group before the first session of the exercise program and one day after the last session after they have completed the 8-week exercise program. Evaluation parameters; 6-minute walk test, fatigue severity scale, stroop test, skinfold, tape measure, comprehensive respiratory function test device (MasterScreen™ Body Plethysmography), Turkish version of the functional outcomes of the disease-specific quality of life sleep questionnaire (functional outcomes of sleep questionnaire, FOSQ,tr) The nottingham health profile includes the Epworth sleepiness scale.

Conclusion: The effects of aerobic and high-intensity interval training training will be interpreted by comparing the evaluations before and after treatment and between groups.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients diagnosed with moderate (AHI:16-30) and severe (AHI>30) OSAS bypolysomnography.
Patients who are inactive according to the International Physical ActivityQuestionnaire-Short Form
Patients with symptoms of Obstructive Sleep Apnea Syndrome (snoring, respiratoryarrest, and daytime sleepiness).

Exclusion

Exclusion Criteria:

Conditions that may make exercise dangerous. Patients with angina pectoris, congestiveheart failure, cardiomyopathy, coronary artery disease, emphysema, inflammatory andmalignant lung disease, pneumothorax.
Those with chronic obstructive pulmonary disease
Those who have recently had upper respiratory tract surgery.
Those with cooperation problems that would prevent the subject from successfullyparticipating and completing the protocol, such as serious neurological,psychological, and medical problems.
Uncooperative patients.
Patients who previously received continuous positive airway pressure therapy
Behavior therapy training.
Patients already taking an exercise program.
Patients who cannot exercise due to musculoskeletal disorders.

Study Design

June 08, 2022

December 20, 2023

Study Description

Obstructive sleep apnea syndrome (OSAS) is a condition characterized by recurrent episodes of partial or complete obstruction of the upper airway (URI) during sleep. It results in recurrent awakenings and episodic oxyhemoglobin desaturations due to decreased ventilation. Clinical manifestations of the disease are snoring, witnessed apnea, suffocation, night sweats, nocturnal arrhythmias, excessive daytime sleepiness, personality changes, morning headache, decreased decision-making ability, forgetfulness, anxiety, depression, cardiovascular diseases, hypertension, myocardial infarction, cardiac It encompasses a wide spectrum of insufficiency, metabolic dysfunction, and cor pulmonale. There are 3 main causes of upper respiratory tract obstruction. These are the tone of the pharyngeal muscles, negative pressure during inspiration and the anatomical structure of the URI. Pharyngeal obstruction plays the most important role. The pharynx can be thought of as a tube devoid of a bony roof, and its opening is determined by the balance between the forces in the closing direction (such as negative intraluminal pressure and externally compressing adipose tissue) and the dilator muscles.

Connect with a study center

Inonu University, Turgut Özal Medical Center, Department of Chest Diseases, Pulmonary Rehabilitation unit
Malatya, 44000
Turkey
Active - Recruiting

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