Using Cardiopulmonary Exercise Test as an Incentive to Outpatient Cardiac Rehabilitation for Acute Coronary Syndrome Survivors.

Last updated: September 2, 2025
Sponsor: Taichung Veterans General Hospital
Overall Status: Completed

Phase

N/A

Condition

Angina

Chest Pain

Heart Disease

Treatment

information reveal

Clinical Study ID

NCT05401240
CE22225A
  • Ages > 20
  • All Genders

Study Summary

Exercise-based cardiac rehabilitation is a class I recommendation for acute coronary syndrome (ACS) patients. However, participate rate of outpatient rehabilitation is quite low and remains a global issue. The study is to propose a strategy in order to encourage post-ACS patients to participate in the outpatient cardiac rehabilitation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • acute coronary patients

Exclusion

Exclusion Criteria:

  • acute illness that stayed in hospital for more than 2 weeks.

  • patients who received surgical intervention

  • severe complications (ex. respiratory failure, stroke, acute renal failure)

  • contraindications of cardiopulmonary exercise testing

  • patients who cannot perform the cardiopulmonary exercise testing

Study Design

Total Participants: 200
Treatment Group(s): 1
Primary Treatment: information reveal
Phase:
Study Start date:
September 01, 2022
Estimated Completion Date:
December 31, 2024

Study Description

Background: exercise-based cardiac rehabilitation is a class I recommendation for acute coronary syndrome (ACS) patients. However, participate rate of outpatient rehabilitation is quite low and remains a global issue. The study is to propose a strategy in order to encourage post-ACS patients to participate in the outpatient cardiac rehabilitation.

Hypothesis: cardiopulmonary exercise test (CPET) incentives ACS survivors to participate in outpatient cardiac rehabilitation.

Objectives: 200 ACS survivors who are eligible for cardiac rehabilitation will be allocated randomly into control and experimental groups.

Method: before discharge, both control and experimental groups will be informed of the importance of cardiac rehabilitation and invited to participate the outpatient rehabilitation. The experimental group will also be told that an important examination, i.e. the CPET, will be performed in order to evaluate their heart function at the outpatient department (OPD).

Primary outcome: the presence of ACS survivors at the OPD of rehabilitation in order to receive the rehabilitation/CPET.

Secondary outcomes: the adherence to cardiac rehabilitation, defined as completing a full course of cardiac rehabilitation (6 sessions) or home-based exercise.

Factors that might influence the presence of ACS survivors at OPD of rehabilitation will also be recorded and analyzed, including:

  • Patient characteristics: age, sex, body mass index (BMI), cardiovascular disease (CVD) risk factors

  • Electrocardiography (ECG): ST elevation myocardial infarction (STEMI) or non ST elevation myocardial infarction (NSTEMI)

  • Lab data: peak troponin level.

  • Days of hospitalization. Statistics: t-test, ANOVA

Connect with a study center

  • Taichung Veterans General Hospital

    Taichung 1668399, Taiwan 7280291 407
    Taiwan

    Site Not Available

  • Taichung Veterans General Hospital

    Taichung, 407
    Taiwan

    Site Not Available

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