Phase
Condition
Cerebral Palsy
Treatment
Stochastic Resonance Electric Stimulation
Clinical Study ID
Ages 10-21 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria for individuals with CP:
Age 10-21
Diagnosis of CP
GMFCS level I-II
Ability to stand up from a chair and start walking.
Migration index of proximal hip (MIGR) < 40% femoral head covering in acetabulum
At least 0° passive dorsiflexion range of motion (ROM)
Sufficient visuoperceptual, cognitive and communication skills
Seizure-free or well-controlled seizures
No other neurological or musculoskeletal disorders (e.g. dystonia, severe scoliosis, hip instability
Ability to communicate pain or discomfort
Ability to assent/consent or obtain parent/guardian consent
Exclusion Criteria for individuals with CP:
Scoliosis with primary curve > 40%
Spinal fusions extending into pelvis
Lower Extremity joint instability or dislocation
Severe tactile hypersensitivity
Lower extremity botulinum injections in the past 6 months
Implanted medical device or metal contraindicative of the application of SR
Pregnancy (self-reported)
Severe lower extremity spasticity (Modified Ashworth Scale score of 4 or greater)
History of pulmonary disease limiting exercise tolerance (Asthma Control Test screen)
History of cardiac disease (American Heart Association screen)
Severely limited range of joint motion/ irreversible muscle contractures
Lower extremity surgery or significant injury within last 1 yr.
Inclusionary criteria for typically developing volunteers:
Aged 10-21 years old
Ability to stand up from a chair and start walking without an assistive device or orthoses
Able to communicate discomfort during testing and can follow multi-step directions
Has not been diagnosed with any neurological or balance disorders
Seizure-free
Exclusionary criteria for typically developing volunteers:
Diagnosis of CP
Significant scoliosis with primary curve > 40°
Lower extremity surgery or fractures in the year prior testing
Joint instability or dislocation in the lower extremities
Severe tactile hypersensitivity
A history of selective dorsal root rhizotomy
Botulinum toxin injections in the lower extremities within the past 6 months
Marked visual or hearing deficits
Any embedded metal that may be contraindicated with application of SR
Severe spasticity of the lower extremity muscles (eg. a score of 4 on the Modified Ashworth)
Pregnancy (self-reported)
Severely limited joint range of motion/ irreversible muscle contractures that would not be candidates for soft-tissue surgery
Learning disabilities
History of neurological disorders
Balance and/or postural impairment
Study Design
Connect with a study center
University of Delaware
Newark, Delaware 19713
United StatesActive - Recruiting
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