Comparative Study for the Evaluation of a New Medical Device on the Treatment of Head Lice Infestation

Inclusion Criteria:

1. Healthy subject;
2. Sex: male or female;
3. Age: 2 years and above;
4. Subject with a slight to moderate lice infestation
5. Subjects with various hair type (from 1 to 3C - hair scale) and hair length (fromshort to mid length hair, not exceeding shoulder)
6. Documented oral informed consent for all subjects, including minors, given freely andexpressly before the start of the study
7. Written informed consent for subjects ≥18 years or legal guardian for subjects< 18years given freely and expressly before start of the study;
8. Written assent for subjects ≥12 to <18 years.
9. Subject/Subject's legal guardian is psychologically able to understand the studyrelated information and to give written informed consent;
10. Females of childbearing potential must have a negative pregnancy test before thebeginning of the study

Exclusion Criteria: In terms of population

1. Pregnant (confirmed by pregnancy test for women of childbearing potential) or nursingwoman or planning a pregnancy during the study;
2. Subject who had been deprived of their freedom by administrative or legal decision oradult subject who is under guardianship;
3. Subject in a social or sanitary establishment;
4. Subject in an exclusion period from a previous study or who is currently participatingto another study on hair/scalp or who participated to another clinical study onhair/scalp within 3 months before first visit.
5. Subject suspected to be non-compliant according to the Investigator's judgment.
6. Subject with curly or frizzy hair (type 4a to 4c in the hair type scale above)
7. Subject with hair length below the shoulder.
8. Subjects with more than 24 lice on the head In terms of associated pathology
9. Subject suffering from a severe or progressive disease or any other pathology that mayinterfere with the evaluation of the study results.
10. Subject with a cutaneous disease on the studied zone (scalp and hair).
11. Subject with severe scratches or open wounds/skin damages on the scalp (lice bitesallowed however).
12. Subject with a known or suspected allergy to any of the components/materials of theinvestigational or comparator devices, anti-lice comb or post-treatment shampoo.
13. Subject who has diabetes (type 1 or 2).
14. Subject with known or suspected immune deficiency or autoimmune disease. Relating to previous or ongoing treatment
15. Subject undergoing a topical treatment on the test area or a systemic treatment with :

• anti-inflammatory medication and/or anti-histamines during the previous 2 weeksand during the study;
• corticosteroids during the 2 previous weeks and during the study;
• retinoids and/or immunosuppressors during the 3 previous months and during thestudy;
• any medication stabilized for less than one month.

16. Subject who received an anti-lice treatment in the previous 2 months.