Microbial Colonization of Dairy Free Oral Probiotics

Last updated: May 11, 2022
Sponsor: John Hale
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT05375396
BLTCT2022/4
  • Ages 18-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of this study is to evaluate the colonization efficacy of probiotic lozenges containing dairy and dairy free probiotic Streptococcus salivarius M18, in healthy adults

Eligibility Criteria

Inclusion

Inclusion criteria: Male or Female 18y - 80y age

  1. In general good health 18 - 80 years of age.
  2. Practice good oral hygiene.

Exclusion

Exclusion criteria:

  1. Have a history of autoimmune disease or are immunocompromised.
  2. Are on concurrent antibiotic therapy or regular antibiotic use within last 1 week
  3. History of allergy (e.g. dairy).

Study Design

Total Participants: 30
Study Start date:
June 01, 2022
Estimated Completion Date:
August 01, 2022

Study Description

This is a double-blind, randomized controlled colonization pilot study with no cross over to evaluate the colonization efficacy of two different lozenges containing either dairy or dairy free probiotic bacteria Streptococcus salivarius M18.

Participants will be randomly assigned to one of the 2 groups consuming probiotic lozenge containing dairy free Streptococcus salivarius M18 or dairy based Streptococcus salivarius M18 over a seven day period. Saliva samples will be collected at predetermined time points pre and post intervention. Colonization efficacy will be determined by enumerating the probiotic in the saliva samples using standard microbiological techniques.

Connect with a study center

  • Blis Technologies Ltd

    Dunedin, Otago 9012
    New Zealand

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.