Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Inclusion Criteria:

• Type 2 diabetes under treatment with HbA1c 6.0-10.0% at screening visit

• Male or female of 20 years or over

• Mixed dyslipidemia: triglyceride 200~499 mg/dL, HDL-cholesterol male ≤45 mg/dL orfemale ≤50 mg/dL

• Identified carotid artery plaque: carotid intima-media thickness (cIMT) ≥ 1.0 mm

• Creatinine ≤1.8 mg/dL

Exclusion Criteria:

• Dyslipidemia which requires other therapy: triglyceride ≥500 mg/dL orLDL-cholesterol ≥190 mg/dL

• Uncontrolled hypertension

• Severe renal dysfunction

• GOT/GPT >120/120 or chronic liver disease

• Pregnant or childbearing woman who does not have enough contraception

• Changes of medication related to chronic diseases (diabetes, hypertension,dyslipidemia, etc.) within 3 months

• Other antiplatlet medication such as cilostazol, clopidogrel (except aspirin)