High Intensity PreHab Before Major Abdominal Surgery

Last updated: March 24, 2025
Sponsor: Medical University Innsbruck
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Individualized high intensity preoperative fitness training

Clinical Study ID

NCT05355909
PreHab in abdominal Surgery
  • Ages 18-99
  • All Genders

Study Summary

The risk for major cardiac cardiovascular events (MACE) within the first 30 day after surgery is nit only associated to the patient relate risk factors but also to the kind of surgery. Surgical interventions can be distinguished infield risk (MACE <1%), moderate risk (MACE 1-5%) and high risk (MACE > 5%). In addition with patient related risk factors it can raise to values of 40%.

The preoperative aerobic fitness [oxygen uptake (VO2) at the ventilatory anaerobic threshold (VAT) <11 mL/kg/min] has been shown of particularly interest in identifying patients at increased risk of postoperative complications. In the last decade major interest was put in the question whether a preoperative personalised physical training may have beneficial effect on the preoperative fitness and on the occurrence of postoperative complications. In some small studies this benefit has been shown for abdominal and thoracic surgery.

However some of those studies are controversially discussed because of missing randomisation and methodical issues. Also most of the studies needs a four week training period. This may lead to ethical and logostical problems oncologic patients.

The aim of this study is to assess the effect of a personalised, high intensity trains program of two weeks on the preoperative fitness.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • ASA I-III

  • BMI 18 - 35kg/m2

  • Signed informed consent

  • Elective abdominal surgery with moderate to high risk

Exclusion

Exclusion Criteria:

  • Pregnancy of lactation

  • Major trauma or massive haemorrhage with the last two weeks

  • Inclusion of the patient in a interventional study

  • Contraindication for preoperative fitness training or ergometry

  • Transplantation surgery

Study Design

Total Participants: 60
Treatment Group(s): 1
Primary Treatment: Individualized high intensity preoperative fitness training
Phase:
Study Start date:
August 01, 2022
Estimated Completion Date:
December 31, 2026

Study Description

The risk for major cardiac cardiovascular events (MACE) within the first 30 day after surgery is nit only associated to the patient relate risk factors but also to the kind of surgery. Surgical interventions can be distinguished infield risk (MACE <1%), moderate risk (MACE 1-5%) and high risk (MACE > 5%). In addition with patient related risk factors it can raise to values of 40%.

The preoperative aerobic fitness [oxygen uptake (VO2) at the ventilatory anaerobic threshold (VAT) <11 mL/kg/min] has been shown of particularly interest in identifying patients at increased risk of postoperative complications. In the last decade major interest was put in the question whether a preoperative personalised physical training may have beneficial effect on the preoperative fitness and on the occurrence of postoperative complications. In some small studies this benefit has been shown for abdominal and thoracic surgery.

However some of those studies are controversially discussed because of missing randomisation and methodical issues. Also most of the studies needs a four week training period. This may lead to ethical and logostical problems oncologic patients.

The aim of this study is to assess the effect of a personalised, high intensity trains program of two weeks on the preoperative fitness.

Connect with a study center

  • Medical University Hospital

    Innsbruck, Tyrol 6020
    Austria

    Active - Recruiting

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