Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

Last updated: May 23, 2024
Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

N/A

Treatment

Standard of Care Pain Control

cryoanalgesia

Clinical Study ID

NCT05348447
2021-238
  • Ages > 18
  • All Genders

Study Summary

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection.

There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients 18 year and older.

  2. Undergoing elective minimally invasive (VATS or robotic) lung resection for nodules (wedge resection, segmentectomy, lobectomy).

  3. Performance status of 1 or 2.

Exclusion

Exclusion Criteria:

  1. Patients with ejection fraction less than 40%

  2. Patients with creatinine greater than 1.5.

  3. Patients with Child's B or C cirrhosis

  4. Patients on chronic narcotics for other reasons

  5. Patients diagnosed with fibromyalgia

  6. Patients who had previous thoracic surgery on the same side.

  7. Patients who cannot communicate in English.

  8. Patients unable to provide informed consent for the study.

Study Design

Total Participants: 110
Treatment Group(s): 2
Primary Treatment: Standard of Care Pain Control
Phase:
Study Start date:
April 21, 2022
Estimated Completion Date:
July 07, 2025

Connect with a study center

  • AHN Allegheny General Hospital

    Pittsburgh, Pennsylvania 15212
    United States

    Site Not Available

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