DermaClose DUKE Fasciotomy and Wound Study

Inclusion Criteria:

• Patient is at least 18 years of age at the time of consent.

• Patient with a full thickness acute wound(s) of the skin:

1. On either the upper or lower extremity (including four-compartment legfasciotomy), in whom DermaClose and/or DermaClose XL is applied during surgery,OR

2. Undergoing a four-compartment leg fasciotomy requiring conventional wounddressing.

• Patient has signed a written informed consent form (ICF) per 21 Code of FederalRegulations (CFR) Part 50.55(e).

Exclusion Criteria:

• Patient in whom the product was used off-label (except for patients who have thedevice on for longer than 14 days)

• Patient with wound(s) that exhibit any of the following:

• Ischemic tissue,

• Infected tissue,

• Acute burned tissue,

• Fragile tissue at the edges of the wound(s).

• Patient, who in surgeon's opinion, does not fit the criteria for this study.