Phase
Condition
Alcohol Use Disorder
Substance Abuse
Addictions
Treatment
Intranasal placebo
Intranasal oxytocin
Clinical Study ID
Ages 21-60 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Heavy alcohol drinkers.
Able to understand/complete questionnaires and procedures in English.
Have venous access sufficient to allow blood sampling.
Exclusion
Exclusion Criteria:
Latex allergy.
Nasal condition that compromises delivery and/or absorption of intra-nasal oxytocin
Pregnant or breast-feeding women.
Desire to be treated for any substance use disorder or court ordered to not drinkalcohol
Medical disorders or other conditions such as alcohol withdrawal seizures ordelirium tremens that may influence study outcome or participant safety.
Positive urine drug screen for amphetamines/ methamphetamines, barbiturates,benzodiazepines, cocaine, opiates, or phencyclidine if determined by the PI toadversely affect participant safety or data integrity.
Medications (past 30 days) that could influence participant safety or data integrity (e.g. antidepressants, antipsychotics, benzodiazepines, etc.) as determined by thePI.
DSM 5 Disorders (other than alcohol) or current/history of neurological disease ofcerebral origin, or head injury with > 20 min loss of consciousness, if determinedby the PI to affect participant safety or data integrity.
Positive breath alcohol reading at beginning of the experimental session.
Actively suicidal (for example, any current suicidal intent, including a plan) orare at serious suicidal risk, by clinical judgment of the PI.
Any condition for which the PI and investigative team determine it is unsafe or notprudent to enroll a participant.
Study Design
Study Description
Connect with a study center
University Hospital
Indianapolis, Indiana 46202
United StatesSite Not Available
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