The Effect of Breathing Exercise on Chemotherapy-induced Nausea and Vomiting in With Autologous Hematopoietic Stem Cell Transplantation Patients

Last updated: March 5, 2024
Sponsor: Istanbul University - Cerrahpasa (IUC)
Overall Status: Completed

Phase

N/A

Condition

Stomach Discomfort

Colic

Vomiting

Treatment

Breathing exercise group

Control group

Clinical Study ID

NCT05311371
2022.065.IRB1.034
  • Ages 18-70
  • All Genders

Study Summary

Nausea and vomiting are serious problems in patients undergoing autologous stem cell transplantation. It is stated that the incidence of acute and delayed nausea and vomiting is more than 50%, even if the patient has been given antiemetic prophylaxis during the treatment process.

Breathing is the easiest relaxation exercise applied during the flow in everyday life and also one of the most important and essential parts of other relaxation exercise. The handbooks prepared for the patients undergoing chemotherapy recommend deep breathing exercises in order to prevent their nausea and vomiting.

The aim of this study is to determine the effect of respiratory exercise on chemotherapy-induced nausea and vomiting in patients with autologous hematopoietic stem cell transplantation.

Research Hypotheses Ho: Respiratory exercise is not effective in preventing chemotherapy-associated nausea and vomiting in autologous hematopoietic stem cell transplant patients.

H1: Respiratory exercise is effective in preventing chemotherapy-associated nausea and vomiting in autologous hematopoietic stem cell transplant patients.

In the literature, no study has been found investigating the effect of breathing exercises on chemotherapy-induced nausea and vomiting for autologous hematopoietic stem cell transplantation patients.

The aim of this study is to determine the effect of respiratory exercise on chemotherapy-induced nausea and vomiting in patients with autologous hematopoietic stem cell transplantation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Least 18-years-old,
  • Autologous hematopoietic stem cell transplantation and take high-dose chemotherapy,
  • not have any communicative problems,
  • not have Coronavirus disease (COVID-19) disease or respiratory disease,
  • Hb value of 10 and above and
  • knowing how to read, write, and speak Turkish

Exclusion

Exclusion Criteria:

  • have respiratory disease and Coronavirus disease (COVID-19),
  • having any communication and psychiatric problem,
  • not knowing how to read, write, and speak Turkish,
  • not wanting to participate in the study and have anemia.

Study Design

Total Participants: 70
Treatment Group(s): 2
Primary Treatment: Breathing exercise group
Phase:
Study Start date:
February 01, 2022
Estimated Completion Date:
March 01, 2023

Connect with a study center

  • Koç University Hospital

    Istanbul, 34025
    Turkey

    Site Not Available

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