Optimizing Engagement in Services for First-Episode Psychosis

Last updated: March 22, 2024
Sponsor: California State University, San Bernardino
Overall Status: Active - Recruiting

Phase

N/A

Condition

Schizophrenia And Schizoaffective Disorders (Pediatric)

Schizotypal Personality Disorder (Spd)

Treatment

Treatment As Usual

Behavioral Activation for First Episode Psychosis

Clinical Study ID

NCT05310838
IRB-FY2020-167
K23MH119313
  • Ages 15-35
  • All Genders

Study Summary

This study will compare a 12-session behavioral activation (BA) intervention modified for first-episode psychosis (FEP) to usual community mental health care (i.e., treatment-as-usual; TAU) delivered over 6 months with a sample of Latinos with FEP and their families. Comparable family group sessions will also be delivered to participants in both conditions. It is expected that BA participants will show better engagement than TAU participants.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Self-identification as Latino
  • Age 15 to 35
  • Diagnostic & Statistical Manual of Mental Disorders-5 diagnosis of schizophrenia,schizoaffective disorder, schizophreniform disorder, brief psychotic disorder, otherspecified schizophrenia spectrum, affective psychosis, and other psychotic disordercriteria
  • Ability to speak English or Spanish
  • Caregiver willing to consent to participate in the study and care
  • Ability to provide fully informed consent

Exclusion

Exclusion Criteria:

  • Diagnosis of psychotic disorder due to another medical condition orsubstance/medication-induced psychotic disorder
  • Presence of a serious medical condition
  • 3≤ years after the onset

Study Design

Total Participants: 58
Treatment Group(s): 2
Primary Treatment: Treatment As Usual
Phase:
Study Start date:
March 01, 2022
Estimated Completion Date:
February 28, 2026

Study Description

After an initial pre-screen, screening, and pre-intervention assessment, enrolled participants will be randomized to either BA or TAU. The study intervention phase will last up to 6 months, during which time BA participants will receive up to 12 one-on-one BA sessions and TAU participants will receive the usual care (e.g., medication management and any other service [e.g., group counseling]). Participants will be assessed at post-intervention, 1-month-post-intervention, and 6-month-post-intervention. The primary objective of aim 1 is to examine whether BA for FEP improves engagement in services better than TAU among Latinos with FEP and their families. Secondary objectives of aim 1 are to examine whether BA participants show greater improvements in quality of life, symptoms (e.g., psychosis, depression), functioning, and recovery compared to TAU participants, and whether BA participants have greater remission rates than the TAU group at 1- and 6-month post-intervention. Additionally, the association between potential BA mediators and engagement will be examined to identify mechanisms of engagement. Potential predictors of engagement will also be examined.

Connect with a study center

  • San Fernando Mental Health Center

    Granada Hills, California 91344
    United States

    Active - Recruiting

  • Olive View - UCLA Medical Center

    Sylmar, California 91342
    United States

    Active - Recruiting

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