CDC reports that in the USA, the prevalence of obesity was 40% in adults between 20 and 39
years, 44.8% in adults between 40 and 59 years, and 42.8% in people 60 years and older.
Furthermore, the CDC emphasized that 49.6% of non-Hispanic Black adults exhibited the highest
age-adjusted prevalence of obesity, which is followed by the occurrence of 44.8% in Hispanic
adults, 42.2% in non-Hispanic White adults, and 17.4% in non-Hispanic Asian adults.
Obesity-related conditions include diverse cardiovascular diseases and dysfunctions, stroke,
Type 2 Diabetes, and certain types of cancer that are some of the leading causes of
preventable, premature death. The estimated annual medical cost of obesity in the United
States was $147 billion in 2008 US dollars; the medical cost for people who have obesity was
$1,429 higher than those of normal weight. Overall, the obesity epidemic is increasing at an
alarming rate worldwide. Because of the alarming rise in the global obesity epidemic, the
terminologies "weight loss" and "weight management" have become common descriptors, even in
the medical and scientific communities. However, the correct scientific terminology should
more accurately refer to express changes in body composition and size, especially in regard
to a reduction in fat mass, rather than weight reduction alone. In fact, the investigators
will demonstrate that focusing on "weight" as an appropriate measuring criterion constitutes
a contradiction and a misconception to the natural sequence of metabolic events in the body
recomposition process. Overall, the term 'weight loss' is an unreliable metric as it
automatically places the primary focus on the heaviness of the body and does not provide a
correct and accurate perspective for evaluating healthy changes in metabolism, body
composition, or size. For example, losing a small amount of fat while increasing muscle
density, strength, and performance could result in a small increase in weight, as muscle is
heavier than fat. It is especially important to highlight that fat is the lightest of
pertinent macro molecules in the human body, lighter than water, muscle mass, and bone.
Moreover, fat is usually 'the last to go' in the body recomposition process, therefore,
creating short-term expectations in weight loss is erroneous and maybe even fraudulent.
A more comprehensive and accurate approach therefore is to fundamentally restore healthy
efficient aerobic metabolism, improving oxygen utilization and management that enables
competent cellular waste removal. Adversarial factors to that objective involve nutrient
deprivation (the most common factor employed by weight loss products and programs), the
imposition of various types of stimulants inducing, via feedback, regulatory
energy-conserving retaliation in the form of even greater survival insurance storage;
triggering the "yo-yo" rebound weight regain. Moreover, conventional weight loss tactics seem
to ignore the biological, genetic, and metabolic consequences that occur with aging.
Diminishing hormonal potencies are crucially important considerations that need to be
addressed in the obesity epidemic. Cellular oxygen deprivation-induced anaerobic pathologies
exacerbate and amplify the effects of diminished hormone functionality and contribute to an
increasingly sluggish metabolism with increased fat, glycogen, and water storage. This also
increases the detrimental strain on the cardiovascular system, kidneys, GI tract, and
microbiome to name a few. The objective is to restore optimal systemic aerobic metabolism
using a novel TRCAP21 nutraceutical formulation that addresses multiple biological pathways
in order to reduce survival panic, restore survival safety, and correct metabolic
homeostasis.