Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients

Inclusion Criteria:

1. Subject ≥25 years.

2. Subject has signed and dated the informed consent form prior to any studyprocedures.

3. History of either a healed edentulous area or single or multiple teeth requiringextraction and in need of a single or fixed bridge prosthetic restoration and whereimmediate restoration/loading is preferred.

4. Opposing jaw in the treatment area meets any of the following stable occlusalconditions:

Complete denture Partial removable denture Fixed bridges and/or crowns Natural dentition

Exclusion Criteria:

Any of the following is regarded as a criterion for exclusion from the study (all criteria apply at study inclusion, but criteria numbered 1-4 also apply during the entire study period):

1. Unlikely to be able to comply with study procedures, according to the Investigator'sjudgment.

2. Subject is not willing to participate in the study or not able to understand thecontent of the study.

3. Involved in the planning and conduct of the study.

4. Unable or unwilling to return for follow-up visits for a period of 5 years.

5. Has an uncontrolled pathological process in the oral cavity (e.g. untreatedperiodontal disease, uncontrolled caries, severe malocclusion, etc.).

6. Known or suspected current malignancy.

7. History of radiation therapy in the head and neck region.

8. History of chemotherapy within 5 years prior to surgery.

9. Systemic or local disease or condition that could compromise post-operative healingand/or osseointegration (e.g., uncontrolled diabetes mellitus as reported by thesubject).

10. Use of systemic corticosteroids, IV bisphosphonates or any other medication thatcould compromise post-operative healing and/or osseointegration.

11. Current alcohol and/or drug abuse.

12. Smoking more than 10 cigarettes of any type per day.

13. Current need for major bone grafting and/or augmentation in the planned implant area (esthetic augmentation and minor facial grafting are allowed).

14. Known pregnancy, or plans to become pregnant during the study period of 5 years

15. Participation in another clinical study within the previous 6 months that mayinterfere with the present study. Post-surgical Exclusion criteria

16. Insufficient primary stability, as judged by the investigator, of the implant(s).

17. Severe non-compliance to CIP as judged by the Investigator and/or Dentsply SironaImplants.