Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.

Inclusion Criteria:

• Male or female patients ≥18 years with the capacity to consent.

• Subjects with a post-stroke medium to severe focal upper limb spasticity for atleast 6 months. Medium to severe focal upper limb spasticity is defined as MAS ≥2 inthe PTMG and DAS ≥2 in the PTT.

• Cohort according to SMART guidelines. The SMART injection concept is designed to beused only in patients suffering from simple patterns ("easy to diagnose spasticitypattern") of adult ULS, where Abobotulinumtoxin-A (AboBoNT-A) (Dysport®) injectioncan be simplified, by recognizing common spasticity patterns and key muscles forinjection, identifying those muscles by palpation, and appropriate injection pointsof the suggested muscles using anatomic landmarks.

• Subjects with treatment goals as reduction of pain, reduction of muscle tone,improvement of care (hygiene/dressing) and/or improvement of passive motion.

• Subjects with the intention to be treated with Dysport® according to the currentlocal Summary of Product Characteristics (SmPC) (Germany) and injection according toSMART must be taken prior to the entry in the study.

• Physiotherapy should remain unchanged within 4 weeks before study start.

Exclusion Criteria:

• Patients treated with intrathecal Baclofen or BoNT-A within the last 6 months

• If treated with oral spasticity medication, change of oral spasticity medicationwithin the last 4 weeks

• Patients with active hand functions or patients with treatment goals of activefunctions.

• Patients with any contraindication for Dysport® according to SmPC.

• Patients in whom SMART therapy is not appropriate (e.g. spasticity pattern otherthan specified in SMART guidelines).

• Participation in an interventional trial at the same time and/or within 3 monthsbefore baseline.

• Diagnosed contracture/contracted muscle.