Nurse AMIE (Addressing Malignancies in Individuals Everyday)

Last updated: April 8, 2025
Sponsor: University of Pittsburgh
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Neoplasms

Cancer

Treatment

Nurse AMIE

Usual Care

Clinical Study ID

NCT05221606
STUDY22090133
R01CA254659
  • Ages > 18
  • All Genders

Study Summary

Nurse AMIE 3.0 is testing the effectiveness of an electronic symptom management system on overall survival in people with stage 3 and 4 cancer who live in rural areas.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patient receiving care for their cancer

  2. Age: 18+ years of age

  3. Has stage 3 or 4 cancer, or an unstaged cancer that is considered 'advanced' (greater than stage 2) by their treating oncologist

  4. Must be within six months of initiation of pharmacologic or radiation treatment, forcurative or palliative purposes, from a medical or radiation oncologist

  5. Clinician-rated ECOG function of 0-3

  6. Lives in a county with RUCC code 4 - 9 and/or zip code with RUCA code 4-10

  7. Has access to personal device capable of receiving telephone calls for studyfacilitator check-ins

  8. Fluent in written and spoken English

  9. Sufficient vision/hearing to interact with the tablet and study staff

  10. Clinician-defined life expectancy of 6 months or more

Exclusion

Exclusion Criteria:

  1. Patients with medical or psychiatric conditions documented in the medical record (beyond cancer, its treatments, and its symptoms) that would impair our ability totest study hypotheses (e.g. psychotic disorders, dementia, inability to giveinformed consent, or follow study instructions).

  2. Patients who are participating in any other supportive care or behavioralintervention studies.

  3. Non-English speaking patients will be excluded, as they represent less than 2% ofthe population targeted.

Study Design

Total Participants: 344
Treatment Group(s): 2
Primary Treatment: Nurse AMIE
Phase:
Study Start date:
May 03, 2022
Estimated Completion Date:
March 31, 2027

Study Description

After being informed about the details of the study, including risks and potential benefits, participants who give their informed consent will do baseline measurements. After these measures are collected, participants will be randomly assigned to either receive the computer tablet Nurse AMIE program or a supportive care book. Participants will be asked to complete measurements throughout the course of their active participation, which will last for 2 years.

Connect with a study center

  • UPMC-Butler

    Butler, Pennsylvania 16001
    United States

    Site Not Available

  • UPMC - Greenville

    Greenville, Pennsylvania 16125
    United States

    Site Not Available

  • Penn State Hershey Medical Center

    Hershey, Pennsylvania 17033
    United States

    Site Not Available

  • UPMC - Indiana

    Indiana, Pennsylvania 15701
    United States

    Site Not Available

  • UPMC - New Castle

    New Castle, Pennsylvania 16105
    United States

    Site Not Available

  • UPMC - Northwest

    Seneca, Pennsylvania 16346
    United States

    Site Not Available

  • Mount Nittany Medical Center

    State College, Pennsylvania 16803
    United States

    Site Not Available

  • West Virginia University

    Morgantown, West Virginia 26506
    United States

    Site Not Available

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