Digital Interactive Technologies in Rehabilitation of Post-sroke Patients With Impaired Fine Function of the Hand

Inclusion Criteria:

1. Men or women aged 18 to 70 years after a first-onset IS, early (1-6 months), laterecovery (6-12 months) periods.
2. Supratentorial IS according to MRI of the brain.
3. The severity of UL paresis ranged from a score of 4 to 3 according to the MedicalResearch Council Scale (MRCS).20
4. Spasticity of 2 points or less by the Modified Ashworth Scale (MAS)
5. Cognitive function more than 20 points on the Montreal Cognitive Assessment (MoCA)
6. Affective disorders score less than 11 on the Hospital Anxiety and Depression Scale (HADS)
7. The patient's ability and willingness to comply with the requirements of thisprotocol.

Exclusion Criteria:

1. Concomitant neurological diseases causing decreased muscle strength or increasedmuscle tone in the UL (e.g., cerebral palsy, brain injury).
2. Clinically significant limitation of the passive movement amplitude in the joints ofthe investigated hand, pronounced contracture and deformities of the upper extremity.
3. Use of other DIT, BFB techniques to restore impaired UL function within 30 days priorto the patient Inclusion Visit.
4. Severe visual impairment, decreased visual acuity of less than 0.2 in the worst eyeaccording to the Golovin-Sivtsev Table24.
5. Sensory aphasia, gross motor aphasia.
6. Recurrent stroke.
7. Unstable angina and/or heart attack in previous month.
8. Uncontrolled arterial hypertension.
9. Somatic diseases in decompensation stage.
10. Alcohol abuse, medical marijuana use or soft drug abuse within the 12 months prior tothe Inclusion Visit.
11. Any medical condition, including mental disease or epilepsy that could affect theinterpretation of study results, the study procedures or patient safety.
12. Pregnancy.
13. Lactation.