Use of a Nerve Regeneration Conduit (NerVFIX®) in the Treatment of Nerve Section of the Wrist

Inclusion Criteria:

• Men and women over 18 years of age and under 65 years of age

• One wrist nerve section ( medial, ulnar) with a minimum of 2 mm and maximum gap of 2cm evaluated during the surgical procedure (Sunderland Grade V)

• Inclusion of direct suture with wrapping or nerve defect with NerVFIX for nervejunction

• Poor outcome on the Mackinnon-Dellon scale: < S3

• Within 1 month of the injury or accident event and/or at the time of the injury (emergency procedure)

• Any damaged artery must be repaired

• Patient with no poor vascularization risk (no surgical treatment of vessel section)or no disease linked to poor vascularization.

• Patient who received the study information and provided consent

• Patients who are members or the beneficiary of a national health insurance plan

Exclusion Criteria:

• Breast feeding women or women without effective contraception (if no effectivecontraception: a pregnancy test is mandatory)

• Digital nerve section

• Pregnant or breast feeding women: Women of childbearing age will be asked to undergoa pregnancy test before being enrolled into the study and to use an effective birthcontrol method

• Patient who suffered amputation of the hand in question

• Surgical site infection or necrotic area; tendon and/or bone damage

• Underlying motor or sensory disorder that could compromise the evaluation;inflammatory arthritis causing pain

• Disease that compromises healing such as diabetes, alcoholism or skin disorder

• Vascular disease leading to reduced blood flow or altered microvascularisation suchas Raynaud's disease

• Subjects who are unlikely to follow through with rehabilitation or who could beaddicted to drugs or alcohol; heavy smokers will be asked to stop smokingvoluntarily

• Persons confined by a judicial or administrative decision

• Adults subject to legal protection measures or who are unable to provide theirconsent