Prospective Evaluation of SARS-CoV-2 Antibodies Levels in a Vaccinated Population of Valle de Aburra

Phase

N/A

Condition

Covid-19

Treatment

N/A

Clinical Study ID

NCT05172167

LIME-21-P-02

Ages 18-90
All Genders
Accepts Healthy Volunteers

Study Summary

Recent research evidence shows that levels of antibodies acquierd post vacunation against SARS-Cov-2 decrease over time as well as the efficacy to control the infection, additionally in a multicenter study carried out in 2020 were evidenced differences in the time it took to decrease the antibodies according to the type of vaccine, defined as mRNA or other types of vaccine.

In this study , the variation of the SARS-Cov-2 antibody levels in patients from Valle de Aburrá will be correlated according to the COVID-19 vaccine received.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Adult over 18 years old
The vaccinated patients to be included must have received a complete vaccinationscheme for COVID-19 according to the Ministerio de Salud y Protección Social deColombia
SARS-CoV-2 infection in the last 2 months, verified by rtPCR test

Exclusion

Exclusion Criteria:

Immunocompromised patients
Immunosuppressive treatments, chemotherapy or antiretroviral therapy
Outpatient anticoagulant therapy
For vaccinated people (groups 1 and 2): if have had COVID-19 infection in the last 6months

Study Design

February 02, 2022

April 30, 2022

Study Description

After being informed about the study, all patients giving written informed consent will undergo a serial IgM -IgG COVID-19 antibodies blood test and SARS-Cov-2 PCR by nasopharingeal swab, that will be taken at the beginning of the study and mensually for two months.

During the study will be done an active search for SARS-CoV-2 infections in the vaccinated people cohort, and if it is posible to characterize the variant of SARS-CoV-2 in participants previously vaccinated against this pathogen.

The main objective of this study is to describe the pattern of antibodies blood test based in the type of vaccine and correlated the pattern of antibodies SARS-Cov-2 levels in a population of Valle de Aburrá.

Connect with a study center

Laboratorio Integrado de Medicina Especializada
Medellin, Antioquia 050022
Colombia
Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.