Transperineal Laser Ablation Treatment (TPLA) for Prostate Cancer (PCa) Registry

Last updated: December 6, 2021
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Overall Status: Active - Recruiting

Phase

N/A

Condition

Prostate Cancer

Prostate Cancer, Early, Recurrent

Urologic Cancer

Treatment

N/A

Clinical Study ID

NCT05163197
W21_458
  • Ages > 18
  • Male

Study Summary

Rationale: Transperineal laser ablation (TPLA) treatment for prostate cancer (PCa) is a minimal invasive focal therapy technique studied worldwide to determine its efficacy. In pilot studies it has shown to be a safe and feasible technique and it has potential to preserve continence and potency over current standard radical therapies. However, (long-term) treatment outcomes of TPLA for PCa remain largely unknown. The aim of this international retrospective registry is to collect and combine data on patients treated TPLA for PCa in order to provide data on safety, feasibility, functional and oncological outcomes.

Objective: To assess safety and feasibility of TPLA for PCa, to assess functional and oncological outcomes of TPLA for PCa and to determine baseline patient characteristics in a multicentre cohort.

Study design: This is an international, retrospective observational registry in which data is recorded of patients who have been treated with TPLA for PCa.

Study population: Male patients treated with TPLA for PCa. Main study parameters/endpoints: The primary endpoint of this registry is oncological outcomes of TPLA for PCa. Secondary endpoints are safety, feasibility and functional outcomes of TPLA for PCa.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male, histological-confirmed disease of localized prostate cancer, TPLA treatment forPCa is performed

Exclusion

Exclusion Criteria:

  • Age < 18 years

Study Design

Total Participants: 200
Study Start date:
October 01, 2021
Estimated Completion Date:
October 01, 2027

Connect with a study center

  • Amsterdam University Medical Centers

    Amsterdam,
    Netherlands

    Active - Recruiting

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