Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Healthy Population Aged ≥13 Years Old

Inclusion Criteria:

• Healthy population aged 13 years and above;
• Proven legal identity;
• The subjects and/or guardians can understand and voluntarily sign the informed consentform (For subjects aged 13-17 years, both subjects and guardians need to sign theinformed consent form).

Exclusion Criteria:

• Disease history or vaccine history of chickenpox or shingles;
• Have fever before vaccination, axillary temperature >37.0°C;
• Already pregnant (including a positive urine pregnancy test) or are breastfeeding,planning to get pregnant within 6 months;
• History of severe allergy and asthma, history of allergy to the vaccine or vaccinecomponents, or serious adverse reactions to the vaccine, such as urticaria, dyspnea,angioedema and abdominal pain;
• Congenital malformations or developmental disorders, genetic defects, severemalnutrition, etc.;
• Autoimmune disease or immunodeficiency / immunosuppression;
• Severe chronic diseases, severe cardiovascular diseases, hypertension (adult fieldmeasurement: SBP ≥140mmHg or diastolic blood pressure ≥90mmHg) that could not becontrolled by drugs, diabetes, liver and kidney diseases, malignant tumors, etc.;
• Family history of psychosis,severe neurological disease (epilepsy, convulsions ortwitching) or mental illness;
• Thyroid disease or history of thyroidectomy, asplenia, functional asplenia, aspleniaor splenectomy resulting from any condition;
• Diagnosed abnormal blood coagulation function (eg, lack of blood coagulation factors,blood coagulopathy, abnormal platelets) or obvious bruising or blood coagulation;
• Immunosuppressive therapy, cytotoxic therapy, inhaled corticosteroids (excludingallergic rhinitis corticosteroid spray therapy, acute noncomplicated dermatitissuperficial corticosteroid therapy) in the past 6 months;
• History of alcohol or drug abuse;
• Receipt of blood products within in the past 6 months;
• Participating in other drug/vaccine clinical trial;
• Receipt of attenuated live vaccines in the past 28 days;
• Receipt of inactivated or subunit vaccines in the past 7 days;
• Onset of various acute or chronic diseases within 7 days prior to the study;
• According to the investigator's judgment, the subject has any other factors that arenot suitable for participating in the clinical trial.