Management of Uterine Leiomyomata and Adenomyosis

Last updated: November 30, 2021
Sponsor: Ahmed Ali Mahmoud
Overall Status: Active - Recruiting

Phase

N/A

Condition

Endometriosis

Heavy Bleeding / Heavy Periods

Desmoid Tumors

Treatment

N/A

Clinical Study ID

NCT05153928
12091984
  • Female
  • Accepts Healthy Volunteers

Study Summary

  1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination

  2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • (1) age≥30 years; (4) dysmenorrhea, adenomyosis-associated chronic pain, and/ormenorrhagia.

(3) regular menstrual cycles before administration of norethisterone; (4) no othertreatment for adenomyosis/leiomyomatosis at least for 3 months biopsies and histopathologyfor operated patients;

Exclusion

Exclusion Criteria:

  • (1) pregnant and/or breast-feeding women (2) patients with a ovarian neoplasm, benignovarian cyst including endometrioma, pelvic inflammatory disease or other endocrinediseases.

Study Design

Total Participants: 100
Study Start date:
April 10, 2021
Estimated Completion Date:
December 25, 2021

Study Description

The aim of the present study is:

  1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination

  2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma

Connect with a study center

  • Ahmed Ali

    Assiut,
    Egypt

    Active - Recruiting

  • Maternaty hospital in assiut

    Assiut,
    Egypt

    Active - Recruiting

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