Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP)

Inclusion Criteria: Patient group:

• Woman or man over 18 years old
• With ATTR or AL cardiac amyloidosis with or without carpal tunnel. The diagnosis ofamyloidosis must be proven by a positive myocardial biopsy or diphosphonatescintigraphy.
• Affiliate or beneficiarie of a social security scheme.
• Having signed the free and informed consent. Healthy volunteers:
• Woman or man over 18 years old
• Affiliate or beneficiarie of a social security scheme.
• Having signed the free and informed consent.

Exclusion Criteria: Patient group:

• Patients participating in another clinical study.
• Patients suffering from rheumatoid arthritis or other autoimmune disease (vasculitis,lupus, scleroderma, etc.)
• Patients with a medical history of wrist surgery (exclude the operated side).
• Patients with a contraindication to performing an MRI (pacemaker, etc.)
• Pregnant or breastfeeding women.
• Protected patients: Adults under guardianship, curatorship or other legal protection,deprived of their liberty by judicial or administrative decision. Healthy volunteer:
• Volunteers participating in another clinical study.
• Volunteers suffering from rheumatoid arthritis or other autoimmune disease (vasculitis, lupus, scleroderma, etc.)
• Pregnant or breastfeeding women.
• Volunteer with a contraindication to performing an MRI (pacemaker, etc.)
• Protected volunteers: Adults under guardianship, guardianship or other legalprotection, deprived of their liberty by judicial or administrative decision.