Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis (AMYLOCARP)

Inclusion Criteria:

Patient group:

• Woman or man over 18 years old

• With ATTR or AL cardiac amyloidosis with or without carpal tunnel. The diagnosis ofamyloidosis must be proven by a positive myocardial biopsy or diphosphonatescintigraphy.

• Affiliate or beneficiarie of a social security scheme.

• Having signed the free and informed consent.

Healthy volunteers:

• Woman or man over 18 years old

• Affiliate or beneficiarie of a social security scheme.

• Having signed the free and informed consent.

Exclusion Criteria:

Patient group:

• Patients participating in another clinical study.

• Patients suffering from rheumatoid arthritis or other autoimmune disease (vasculitis, lupus, scleroderma, etc.)

• Patients with a medical history of wrist surgery (exclude the operated side).

• Patients with a contraindication to performing an MRI (pacemaker, etc.)

• Pregnant or breastfeeding women.

• Protected patients: Adults under guardianship, curatorship or other legalprotection, deprived of their liberty by judicial or administrative decision.

Healthy volunteer:

• Volunteers participating in another clinical study.

• Volunteers suffering from rheumatoid arthritis or other autoimmune disease (vasculitis, lupus, scleroderma, etc.)

• Pregnant or breastfeeding women.

• Volunteer with a contraindication to performing an MRI (pacemaker, etc.)

• Protected volunteers: Adults under guardianship, guardianship or other legalprotection, deprived of their liberty by judicial or administrative decision.