Effects of Electroacupuncture With Different Frequencies for Major Depressive Disorder

Inclusion Criteria:

1. Patients suffering from MDD in accordance with the diagnostic criteria;
2. Hamilton Depression Scale score is between 21 and 35 (mild to moderate MDD);
3. 18≤age≤60 years, both gender;
4. Patients who have not used antidepressants and other psychiatric drugs (includingtraditional Chinese medicine), or have used them but have stopped for at least 2weeks;
5. Patients have clear consciousness and could communicate with others normally;
6. Patients could understand the full study protocol and written informed consent isprovided by themselves. Note: Subjects who meet the above six items will be included.

Exclusion Criteria:

1. Patients with bipolar disorder;
2. Patients with schizophrenia or other mental disorders;
3. Patients with severe medical diseases, tumors or diseases of the central nervoussystem;
4. Patients suffering from severe depressive episode with psychotic symptoms;
5. Suicidal patients;
6. Patients with seasonal depression;
7. Patients with organic depression;
8. Patients with alcohol or drug addicts;
9. Patients using other therapies;
10. Patients in pregnancy or lactation;
11. Patients suffering from cognitive dysfunction, aphasia or other diseases that cannotcooperate with treatment;
12. Patients with pacemakers;
13. Patients who are not suitable for electroacupuncture.