CArdioMetabolism and Atherosclerotic PlaqUe progreSsion

Last updated: August 5, 2024
Sponsor: Ruijin Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes Mellitus, Type 2

Cardiac Disease

Diabetes Prevention

Treatment

N/A

Clinical Study ID

NCT05117424
RJH-CAMPUS
  • Ages 18-80
  • All Genders

Study Summary

Systematic metabolic diseases are closely related to prevalence and progression of atherosclerosis. This prospective cohort consecutively enrolls patients with coronary artery disease compliacted with metabolic abnormalities such as diabtetes, prediabetes, obesity, chronic kidney disease and hyperuricemia.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-80 years

  • Established coronary artery disease or metabolic disorders, including:

  1. Type 2 diabetes diagnosed by one of the following criteria:HbA1c >/= 6.5% Fasting plasma glucose >/= 7.0 mmol/l (confirmed) 2h plasmaglucose value during OGTT >/= 11.1 mmol/l Already receiving glucose-loweringagents

  2. Prediabetes

  3. Obesity

  4. Chronic kidney disease

  5. Hyperuricemia

  6. Dyslipidemia

Exclusion

Exclusion Criteria:

  • Severe liver failure (Child-Pugh grade B to C)

  • Severe anemia (hemoglobin < 60g/L)

  • Familial hypercholesterolemia

  • Active malignant tumor

  • Active autoimmune diseases on corticosteroids

  • Acute or chronic infection

  • Life expectancy < 1 year

Study Design

Total Participants: 3000
Study Start date:
January 01, 2017
Estimated Completion Date:
December 31, 2025

Study Description

CArdioMetabolism and Atherosclerotic PlaqUe progreSsion (CAMPUS) study is a single center, prospective cohort study to investigate the impact of cardiometabolic factors on coronary diseases. This study consecutively enrolls patients with coronary artery diseases complicatied with metabolic abnormalities, including diabetes, prediabetes, obesity, chronic kidney disease and hyperuricemia.

Connect with a study center

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, 200025
    China

    Active - Recruiting

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