Medtronic Signia SDR Product Surveillance Registry

Inclusion Criteria:

• Patient or legally authorized representative (LAR) provides authorization and/orconsent per institution and geographical requirements

• Patient has, or is intended to receive or be treated with, an eligible Medtronicproduct

• Patient is consented within the enrollment window of the therapy received, asapplicable

Exclusion Criteria:

• Patient who is, or is expected to be, inaccessible for follow-up

• Patient is excluded by local law

• Patient is currently enrolled in, or plans to enroll in, any concurrent drug/devicestudy that may confound the PSR results