NuVasive® ACP System Study

Inclusion Criteria:

1. Patients who are ≥18 years of age at the time of consent

2. Have planned anterior cervical (C2 to C7) spine surgery using the NuVasive ACPSystem in conjunction with a NuVasive interbody implant or vertebral bodyreplacement device (VBR), or a structural bone allograft spacer, for treatment ofany of the following conditions:

3. degenerative disc disease, as defined by neck pain of discogenic origin withdegeneration of the disc confirmed by patient history and radiographic studies

4. trauma (including fractures)

5. tumors involving the cervical spine

6. cervical spinal deformity (kyphosis, lordosis, or scoliosis)

7. failed previous cervical fusion(s) (e.g., pseudoarthrosis)

8. cervical spondylolisthesis

9. cervical spinal stenosis

10. Able to undergo surgery based on physical exam, medical history, and surgeonjudgment

11. Understands the conditions of enrollment and is willing to sign an informed consentform to participate in the study

Exclusion Criteria:

1. Procedures performed with interbody implants with integrated vertebral body screw(s)

2. Patient is involved in active litigation relating to the spine (worker'scompensation claim is allowed if it is not contested)

3. Use of bone growth stimulators postoperatively

4. Active smoking within 6 weeks of surgery

5. Patient has known sensitivity to materials implanted

6. Systemic or local infection (latent or active) or signs of local inflammation

7. Patient has inadequate bone stock or quality, or a physical or medical conditionthat would prohibit beneficial surgical outcome based on surgeon judgment

8. Pregnant, or plans to become pregnant

9. Patient is a prisoner

10. Patient is participating in another clinical study that would confound study data