ED Observation for Opioid Use Disorder

Inclusion Criteria:

• Is 18 years of age or older

• Is able to speak English sufficiently to understand study procedures

• Has a history of non-medical opioid use

• Is a potential candidate for ED-based MOUD treatment initiation and referral at thesite as confirmed by clinical staff

• s not receiving MOUD through ongoing formal addiction treatment or pain managementat the time of index ED visit

• Is willing to receive either standard ED care or enhanced ED care in EDOU dependingon random assignment

• Presents to the ED during study screening hours

Exclusion Criteria:

• Unwilling or unable to provide written/electronic informed consent/HIPAAAuthorization for research procedures, including research visits at baseline and Day 30 and Day 90, and/or consent for the release of health records and data matchingfor a period of 2 years following enrollment and 1 year prior to enrollment.

• Currently in jail, prison or any inpatient overnight facility as required by courtof law or have pending legal action or that could prevent participation in the study

• Presents from a medical-based extended care facility (e.g., skilled nursingfacility)

• Previous participation in the current study

• Inadequate locator information (unable or unwilling to provide one unique mean ofcontact).

• Has acute, severe medical, psychiatric, or concurrent substance use problem or meetsother criteria that would exclude the patient (clinically) from placement in EDOUaccording to EDOU placement clinical protocols.