Affixus Natural Nail System Humeral Nail PMCF

Inclusion Criteria:

• Patients 18 years or older and skeletally mature.
• Patient must have either a proximal humeral fracture or humeral shaft fracturerequiring surgical intervention and be eligible for fixation by intramedullarynailing.
• Patient has been or is scheduled to be treated with the Affixus Natural Nail SystemHumeral Nail.
• Patient must be able and willing to complete the protocol required follow-up.
• Patient must have a signed Institutional Review Board/Ethics Committee approvedinformed consent. (An Institutional Review Board/Ethics Committee is group that hasbeen formally designated to review and monitor medical research involving humansubjects.)
• Patients capable of understanding the surgeon's explanations and following hisinstructions, able and willing to participate in the follow-up program and who gaveconsent to take part in the study.

Exclusion Criteria:

• Distal fracture involving the olecranon fossa.
• Bone shaft having excessive bow or deformity.
• A medullary canal obliterated by a previous fracture or tumor.
• Active or previous infection.
• Skeletally immature patients.
• All concomitant diseases that can impair the functioning and the success of theimplant.
• Patients with mental or neurologic conditions who are unwilling or incapable of givingproper informed consent and following postoperative care instructions.
• Patient is a vulnerable subject (prisoner, mentally incompetent or unable tounderstand what participation to the study entails, a known alcohol or drug abuser,anticipated to be non-compliant).
• Patient known to be pregnant or breast feeding.
• Likely problems with maintaining follow-up program (e.g. patient with no fixedaddress, long distance, plans to move during course of study).
• Patients who have any condition that would in the judgment of the investigator placethe patient at undue risk or interfere with the study.
• Not expected to survive the duration of the follow-up program.