Last updated: December 28, 2022
Sponsor: First Affiliated Hospital Xi'an Jiaotong University
Overall Status: Active - Recruiting
Phase
N/A
Condition
Epilepsy
Seizure Disorders
Treatment
N/AClinical Study ID
NCT05019404
XJTU1AF2021LSK-194
Ages 18-60 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- male or female aged between 18 and 60 years;
- drug- resistant temporal lobe epilepsy, remaining seizures after two or more toleratedand appropriately chosen antiepileptic drugs;
- monthly or more seizures during the preceding year prior to trial;
- the full- scale intelligence quotient (IQ) more than 70, understanding and completingthe trial;
- signing the informed consent;
- good compliance, at least 12- month follow- up after surgery.
Exclusion
Exclusion Criteria:
- tumor in temporal lobe;
- extratemporal epilepsy and temporal plus epilepsy;
- drug- responsive epilepsy, seizure freedom with current drugs in recent one year;
- pseudoseizures;
- seizures arising from bilateral temporal lobes;
- significant comorbidities including progressive neurological disorders, activepsychosis, and drug abuse;
- a full- scale IQ lower than 70, unable to complete tests;
- previous epilepsy surgery;
- poor compliance and inadequate follow- up.
Study Design
Total Participants: 120
Study Start date:
April 25, 2023
Estimated Completion Date:
September 01, 2025
Study Description
Connect with a study center
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi 710061
ChinaActive - Recruiting
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