Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop

Last updated: April 26, 2022
Sponsor: Tanta University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Gall Bladder Disorders

Treatment

N/A

Clinical Study ID

NCT04961034
33943/7/20
  • Ages < 8
  • All Genders

Study Summary

the study of the effect o the hanging of the jejunal loop to the peri KPE Glisson capsule on the rate of bile drainage and requirement of liver transplantation

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • infants with biliary atresia diagnosed and treated before 60th day of age

Exclusion

Exclusion Criteria:

  • infants older than 60 days

Study Design

Total Participants: 26
Study Start date:
January 01, 2015
Estimated Completion Date:
December 20, 2023

Study Description

To evaluate the effect of anchoring jejunal loop to Glisson capsule of liver after completion of modified Kasai portoenterostomy (KPE) on the frequency of attacks of cholangitis and the overall incidence of native liver survival.

Methods: Retrospective study included 29 infants diagnosed as biliary atresia (BA). They were subjected to modified KPE. Two subgroups were present. Group A included 16 infants and had KPE. Group B included 13 infants and had the assumed modification. Wider dissection of fibrous portal plate was considered in both groups. After completion of KPE, the jejunal loop anchored to Glisson capsule of liver at porta hepatis in group B.

Connect with a study center

  • Tanta University

    Tanta, Gharbeya 31111
    Egypt

    Completed

  • Tantra Universiy

    Tanta, 31512
    Egypt

    Active - Recruiting

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