Epidural Analgesia and Maternal Fever During Labor

Inclusion Criteria:

• Age ≥18 years old;

• Nulliparae with single term cephalic pregnancy;

• Preparing to give vaginal delivery under epidural analgesia.

Exclusion Criteria:

• Basal body temperature ≥37.3°C;

• Presence of serious pregnancy complications (such as severe preeclampsia, placentaaccreta, HELLP [Hemolysis, Elevated Liver enzymes, Low Platelet count] syndrome,placenta previa, abruption of placenta, or hyperthyroidism);

• History of hyperthyrodism, including hyperthyrodism in pregnancy;

• Taking sedatives and/or analgesics within one week before planned delivery;

• American Society of Anesthesiologists classification >class III;

• Contraindications to epidural puncture, including central nervous system diseases (such as poliomyelitis), spinal diseases (such as intraspinal mass, lumbar discherniation, history of spinal trauma, etc.), abnormal blood coagulation, etc.;

• Presence of infections, including obstetric infections, systemic infections (such assepsis, bacteremia), or infections at the puncture site or adjacent sites;

• Other conditions that are considered unsuitable for study participation;

• Refused to participate in the study.