Serious Game-based Interventions in Patients With Mild Cognitive Impairment Outside the Clinic

Last updated: July 12, 2024
Sponsor: University of Massachusetts, Amherst
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mild Cognitive Impairment

Dementia

Memory Loss

Treatment

Neuro-World

Clinical Study ID

NCT04920123
2585
  • Ages > 55
  • All Genders

Study Summary

This study will evaluate the therapeutic efficacy of Neuro-World cognitive training games (Woorisoft, S. Korea) in patients with mild cognitive impairment.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Seventeen points or greater and smaller than twenty-six points on the MontrealCognitive Assessment (MoCA)

  • Fifty-five years old and above

  • Minimal technological literacy (i.e. ability to use a tablet independently)

  • Having a computer for online videoconferencing-based communication (necessary foronline cognitive assessments)

Exclusion

Exclusion Criteria:

  • Confounding neurological and psychiatric disorders

  • History of traumatic brain injury

  • Clinically known hearing or vision impairment

  • Severe upper-limb motor impairments that could impact the use of mobile devices

  • Clinical presentations suggestive of dementia with Lewy bodies, progressivesupranuclear palsy, multiple system atrophy, or vascular parkinsonism

  • Diagnosis of dementia

  • Major depression

  • Any significant upper-limb impairment that could affect tablet use

  • Participation in any other therapist-supervised cognitive training

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Neuro-World
Phase:
Study Start date:
February 17, 2022
Estimated Completion Date:
March 31, 2025

Study Description

This study will be a cross-over randomized controlled trial.

Fifty participants will be enrolled and randomly assigned to group A or group B.

Group A will self-administer Neuro-World cognitive training games for 30 minutes a day, twice a week for 12 weeks in the home setting (i.e., intervention period). For the following 12 weeks, the participants will not engage in any therapist-supervised cognitive therapies (i.e., no-intervention period).

Group B will not engage in any therapist-supervised cognitive therapies (i.e., no-intervention period). For the following 12 weeks, the participants will self-administer Neuro-World cognitive training games for 30 minutes a day, twice a week in the home setting (i.e., intervention period).

All the participants in both groups will receive phone calls twice a week to 1) provide feedback on their adherence to Neuro-World cognitive training (during the intervention period) and 2) learn any significant changes in the level of their daily activities (during the no-intervention period and the intervention period).

Connect with a study center

  • University of Massachusetts, Amherst

    Amherst, Massachusetts 01003
    United States

    Active - Recruiting

  • The State University of New Jersey, Rutgers

    Newark, New Jersey 07102
    United States

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.