A Prediction Model of 28-day Mortality in Septic Shock

Last updated: June 4, 2021
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Sepsis And Septicemia

Low Blood Pressure (Hypotension)

Treatment

N/A

Clinical Study ID

NCT04915625
2021-0603
  • Ages > 18
  • All Genders

Study Summary

This clinical study adopts the design of cohort research, selects the sepsis shock patients admitted to our hospital ICU as the research object, takes the 28-day mortality rate as the outcome index, collects the baseline data of the patient, the severity of the disease, vital signs, the main infection site, the laboratory-related index, the treatment method and other data, screens out the risk factors affecting the sepsis shock 28-day mortality rate and constructs the prediction model accordingly, analyzes the prediction model with the subject's working characteristic curve (ROC). The recognition ability of the model is calculated by the area under the ROC curve (AUC) and the ability of the model to predict 28-day mortality with SOFA and APACHE II.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age ≥ 18 years of age, gender-neutral;
  2. Diagnosed with sepsis shock;
  3. ICU survives longer than 48 h;
  4. The preservation of clinical data is complete;

Exclusion

Exclusion Criteria:

  • Diagnosed with sepsis shock within 6 hours of emergency treatment; Combined with peoplewith autoimmune diseases; 3. Organ transplantation or immunosuppressive treatment; 4.Severe heart, liver and kidney insufficiency; 5. Late stage of malignant tumor; 6.Maternity; 7. Referral or referral to another hospital;

Study Design

Total Participants: 530
Study Start date:
December 01, 2020
Estimated Completion Date:
December 31, 2022

Connect with a study center

  • 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China

    Hanzhou, Zhejiang 310000
    China

    Active - Recruiting

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