Effects of a Fasting Mimicking Diet on Sperm Quality

Last updated: December 28, 2023
Sponsor: Charite University, Berlin, Germany
Overall Status: Completed

Phase

N/A

Condition

Infertility

Male Hormonal Deficiencies/abnormalities

Treatment

Fasting Mimicking Diet

Clinical Study ID

NCT04908774
KiWu-B
  • Ages 18-60
  • Male

Study Summary

This study investigates the effect of repetitive cycles of a Fasting Mimicking Diet (3x5 days in six months) on sperm quality in men

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Men aged between 18 and 60 years
  • Unfulfilled desire to have a child > 1 year
  • reduced sperm quality (proven via spermiogram according tho WHO-5 criteria)
  • informed consent
  • 20 kg/m² <= BMI <= 35 kg/m²

Exclusion

Exclusion Criteria:

  • No sufficient communication possible
  • severely impairing cognitive illness
  • serious mental illness
  • Patients with anatomical/organic damage of reproductive organs
  • Eating disorders in the medical history
  • Serious internal diseases
  • Lack of internet access
  • No consent to randomisation
  • Participation in other studies

Study Design

Total Participants: 22
Treatment Group(s): 1
Primary Treatment: Fasting Mimicking Diet
Phase:
Study Start date:
May 25, 2021
Estimated Completion Date:
October 01, 2023

Study Description

This 2-arm, randomized, controlled exploratory clinical trial aims to explore fasting as a novel supportive treatment in male infertility due to reduced sperm quality according to WHO5-criteria. The participants will be randomized in two groups. The intervention group follows a regime of a periodic fasting mimicking diet (3x5 days in six months, every 6-8 weeks, accompanied via a mobile application), whereas the patients on the waiting list continue their normal diet. Spermiograms are taken about every 2 months following the WHO-5 criteria. In addition, qualitative interviews will be conducted including individual and focus group interviews with a subgroup of participants.

Connect with a study center

  • Hochschulambulanz für Naturheilkunde der Charité-Universitätsmedizin Berlin

    Berlin, 14109
    Germany

    Site Not Available

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