Intravenous Administration of Vitamin B Complex Improves Renal Recovery in Patients with AKI

Last updated: January 28, 2025
Sponsor: Caja Nacional de Salud
Overall Status: Completed

Phase

4

Condition

Renal Failure

Kidney Disease

Kidney Failure

Treatment

STOP AKI protocol

Vitamin B Complex

Clinical Study ID

NCT04893733
VBCNS
  • Ages 18-100
  • All Genders

Study Summary

Animal and human studies have shown that the administration of vitamin B3 (niacin) improves renal ischemia; helping to recover from acute kidney injury (AKI) more effectively; Therefore, its use in patients with AKI could improve short-term outcomes: accelerating the recovery of renal function, reducing the days of hospital stay and costs; as well as reducing the incidence of chronic kidney disease (CKD) or progression of CKD after an episode of AKI.

Our main objective is to determine the usefulness of the administration of vitamin B complex as a treatment for established acute kidney injury and its effect on short and long-term outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients over 18 years of age who meet modified KDIGO criteria for Acute KidneyInjury, based on serum creatinine or urinary volume criteria.

Exclusion

Exclusion Criteria:

  • Patient under 18 years of age

  • Patients with stage G5 chronic kidney disease

  • Patients with chronic kidney replacement therapy.

  • Pregnant women

  • Transplant patients

Study Design

Total Participants: 260
Treatment Group(s): 2
Primary Treatment: STOP AKI protocol
Phase: 4
Study Start date:
September 01, 2020
Estimated Completion Date:
April 30, 2022

Connect with a study center

  • Hospital Obrero No 2 - C.N.S.

    Cochabamba, 0
    Bolivia

    Site Not Available

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