The Effectiveness of Ozone (O2-O3) Injections in the Treatment of Myofascial Pain Syndrome

Last updated: January 14, 2022
Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Overall Status: Completed

Phase

N/A

Condition

Somatoform And Dissociative Disorders

Oral Facial Pain

Fibromyalgia

Treatment

N/A

Clinical Study ID

NCT04885881
14
  • Ages 18-65
  • All Genders

Study Summary

Ozone (O2-O3) has been used as a supportive therapy in various musculoskeletal diseases such as lumbosacral disc herniation, knee osteoarthritis, meniscus injury, shoulder pathologies.The aim of this study is to investigate the effectiveness of ozone (O2-O3) injection applied to the trigger point in the treatment of myofascial pain syndrome.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • diagnosed with myofascial pain syndrome according to the criteria defined by Simons etal.
  • aged between18-65
  • having typical myofascial pain symptoms for at least 3 months

Exclusion

Exclusion Criteria:

  • presence of cervical radiculopathy, cervical myelopathy, severe dyscal or bonydegeneration
  • presence of a history of neck trauma or surgery in the last year
  • presence of trigger point injection for myofascial pain syndrome treatment in the last 3 months
  • presence of cognitive impairment, malignant hypertension, G6PDH (Glucose 6- PhosphateDehydrogenase) deficiency, Graves' disease, chronic recurrent pancreatitis attack,severe thrombocytopenia (platelet value <50,000 / microliter), cerebrovascular diseasein which bleeding is active
  • presence of systemic diseases such as fibromyalgia, inflammatory diseases such asrheumatoid arthritis, polyneuropathy, coagulopathy.
  • presence of pregnancy and breastfeeding

Study Design

Total Participants: 46
Study Start date:
April 15, 2021
Estimated Completion Date:
December 01, 2021

Study Description

The study was designed as a prospective, randomized, controlled trial. Fourty six people who met the inclusion criteria will randomized into two groups of 23 people. The first group will be designated as ozone therapy group and patients in the second group will be designated as the lidocaine injection group. Patients will be evaluated with visuel analog scale (10cm-VAS), Neck Disability Index (NDI), Pain Score (PS) and neck lateral flexion measurement before and after treatment at 4 and 12 weeks.

Connect with a study center

  • Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

    Ankara, 06800
    Turkey

    Site Not Available

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