Culturally Adapted Motivational Interviewing With CBT and Mindfulness Based Relapse Prevention for Substance Use Disorder in Pakistan (CAMIAB)

Last updated: September 3, 2024
Sponsor: Pakistan Institute of Living and Learning
Overall Status: Active - Recruiting

Phase

N/A

Condition

Stimulant Use Disorder

Opioid Use Disorder

Treatment

Motivational interviewing with CBT (MICBT)

Mindfulness based Relapse Prevention (MBRP)

CAMIAB

Clinical Study ID

NCT04885569
PILL-CAMIAB-001
  • Ages > 18
  • All Genders

Study Summary

The study has both quantitative and qualitative components. The aim of study is to:

  1. Culturally adapt and integrate the existing Motivational Interviewing with Cognitive Behavioral Therapy(MICBT) and Mindfulness based Relapse Prevention (MBRP) for people with Substance Use Disorder (SUD) in Pakistan

  2. Test the feasibility and acceptability of the integrated intervention called CAMIAB ('CAMIAB' means success in Urdu) in a randomized control trial (RCT).

Eligibility Criteria

Inclusion

Inclusion Criteria

  • Participants with substance use disorder

  • Meeting DSM-V criteria for substance use disorder

  • Age 18 years and above

  • Being able to understand spoken or written Urdu

  • Have undergone through the process of detoxification before study intervention

Exclusion Criteria

• Any evidence of organic brain disease, clinically significant cooccurring medical illness or mental illness to the extent that can impede their ability to provide informed consent or engagement in the intervention.

Study Design

Total Participants: 260
Treatment Group(s): 3
Primary Treatment: Motivational interviewing with CBT (MICBT)
Phase:
Study Start date:
December 01, 2023
Estimated Completion Date:
June 30, 2025

Study Description

This study aims to culturally adapt the existing Motivational Interviewing with CBT (MICBT) and integrate this with Mindfulness-Based Relapse Prevention (MBRP) intervention for people with SUD and to test the feasibility, and acceptability of the intervention in a randomized control trial (RCT). First phase will be cultural adaptation of intervention through focus groups and individual interviews with key stakeholders . Phase two will be to test integrated MICBT and MBRP on a small group of participants N=12.

Third phase will be a feasibility factorial randomized control trial with 260 participants with SUD (n=65). Participants will be recruited from primary care hospitals and drug rehabilitation centers in Karachi, Lahore, Rawalpindi, Hyderabad, and Peshawar Pakistan. Intervention will take place weekly over a period of 12 weeks. The intervention will consist of individual as well as group sessions. Assessments will be completed at baseline, after completion of intervention (12th week) and 24th week post randomization. All assessments will be administered by masked research assistants (RAs), not involved in delivering intervention sessions. The therapists delivering the intervention will be trained and will be provided ongoing supervisions by a senior therapist.

Connect with a study center

  • Pakistan Recovery Oasis

    Lahore,
    Pakistan

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.