Patient Reported Symptom Control With THC or CBD Use

Last updated: March 30, 2025
Sponsor: M.D. Anderson Cancer Center
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Cancer Pain

Chronic Pain

Neoplasms

Treatment

Electronic Health Record Review

Questionnaire Administration

Clinical Study ID

NCT04875286
2019-0753
NCI-2021-02853
2019-0753
  • Ages > 18
  • All Genders

Study Summary

This study compares patients' attitudes regarding marijuana products for medical use and other treatments for cancer-related pain. This study may help researchers gain better understanding of patient's perception on their use of marijuana products in treating cancer-related pain and other common cancer-related symptoms.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients (inpatient or outpatient) seen by the Palliative Care and IntegrativeMedicine teams at The University of Texas MD Anderson Cancer Center (Texas) and thePalliative Care team at Banner MD Anderson Cancer Center (Arizona)

  • Patients must be primary residents of Texas or Arizona

  • Patients able to speak and read English

  • Patients are 18 years old and above

  • Patients should have a cancer diagnosis, cancer-associated pain, and taking strongopioids (morphine, oxycodone, hydrocodone, hydromorphone, oxymorphone, methadone,fentanyl)

  • Patients who have used in the past 3 months or are using alternative botanical painmanagement while under prescription opioids

Exclusion

Exclusion Criteria:

  • Patients who are not able to speak or read English

  • Altered mental status as determined by the interviewer based on the ability tounderstand the nature of the study and consent process

  • Patients who have not used medical marijuana and/or CBD products

  • Patients who do not have cancer

  • Patients who do not have cancer-associated pain

  • Patients who are not taking opioids

Study Design

Total Participants: 200
Treatment Group(s): 2
Primary Treatment: Electronic Health Record Review
Phase:
Study Start date:
February 03, 2021
Estimated Completion Date:
February 02, 2027

Study Description

PRIMARY OBJECTIVE:

I. To determine the patient's reported preference for cancer pain improvement with opioids, opioids with delta-9-tetrahydrocannabinol (THC)-marijuana and/or opioids with cannabidiol (CBD).

SECONDARY OBJECTIVES:

I. To determine the association between perception of cancer-related symptom relief and use of THC-marijuana and/or CBD.

II. To compare patient perception of THC-marijuana and/or CBD versus (vs.) cancer treatments in treatment of cancer.

III. To evaluate patient report of adverse effects experienced while using THC-marijuana and/or CBD.

IV. To evaluate patient reported concerns while using THC-marijuana and/or CBD. V. To evaluate patient attitude of dosing, forms and use of THC-marijuana and/or CBD.

VI. To evaluate demographic, physical and psychosocial factors that influence patient perception and attitudes of THC-marijuana and/or CBD.

VII. To explore the difference of patient perception of THC-marijuana and CBD in cancer centers in a legalized vs. a non-legalized state.

VIII. To explore the patient reported preference of THC-marijuana and CBD for cancer pain and symptom relief of patients in a Supportive Care Center vs. Integrative Medicine Center at University of Texas (U.T.) MD Anderson.

OUTLINE:

Patients' medical records are reviewed and then complete questionnaires over 27 minutes.

Connect with a study center

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona 85234
    United States

    Site Not Available

  • M D Anderson Cancer Center

    Houston, Texas 77030
    United States

    Site Not Available

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