Bioavailability of Plant Protein Amino Acids

Last updated: November 29, 2023
Sponsor: University of Limerick
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

Red lentil protein concentrate

Non-essential amino acid blend

Whey protein concentrate

Clinical Study ID

NCT04872530
2019_12_02_EHS
  • Ages 18-35
  • Male
  • Accepts Healthy Volunteers

Study Summary

This study aims to inform of the mechanism of action of plant-based protein by measuring the bioavailability (i.e. rate of appearance and magnitude of concentration in the circulation following oral ingestion) of key amino acid and metabolic products that regulate skeletal muscle protein synthesis (MPS) in humans.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • No known intolerance to any item contained in the protein products.
  • No blood borne disease risk, current illness or medication that would adversely affectparticipation
  • No known adverse reaction to venepuncture

Exclusion

Exclusion Criteria:

  • n/a

Study Design

Total Participants: 10
Treatment Group(s): 6
Primary Treatment: Red lentil protein concentrate
Phase:
Study Start date:
January 08, 2020
Estimated Completion Date:
September 29, 2023

Study Description

Plant-based proteins contain several amino acids that are essential to signal muscle growth/repair and act as a substrate during muscle protein synthesis. However, compared to animal protein or free-amino acids, the bioavailability of certain essential amino acids may be compromised. Following selective processing (e.g. removal of carbohydrate and/or other anti-nutritive factors) food grade plant-based protein concentrates possibly confer greater bioavailability and bioactivity in vivo. This project explores the bioavailability and bioactivity of selected plant-based protein concentrates following oral ingestion in young, healthy men and women.

Connect with a study center

  • Education and Health Sciences

    Limerick, V94 T9PX
    Ireland

    Site Not Available

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