68Ga-DOTA-TATE PET/CT Imaging in NETs

Inclusion Criteria:

1. Clinical requisition for a 68Ga-DOTA-TATE PET/CT signed by a referring doctor

2. Patients with suspected or proven tumors expressing somatostatin receptors

3. Informed consent by patient (or parents if patient is less than 18 years of age)

Exclusion Criteria:

1. Pregnancy (not an absolute exclusion). See below.

2. Patient refusal to participate.

3. Prior severe anaphylactic reaction to DOTA-TATE or somatostatin analogs.

• In the case of a diagnostic procedure in a patient who is or may be pregnant,the principle of benefits-disadvantages would be applied following an in-depthdiscussion with the treating physicians and the patient. In this context, anyclinical situation in which the patient's life would be at stake by excludingher from the study would be considered. The conditions to decide whether toinclude the patient would be:
• Severe medical condition involving the life of the pregnant woman and/orthe fetus;
• Existing treatments that are ineffective or may present toxicity to thewoman and/or fetus;
• High clinical suspicion of a somatostatin receptor overexpressing tumour;
• Negative, indeterminate or contraindicated first-line imaging tests;
• Therapeutic gesture considered during pregnancy based on the results ofthe examination, which may include termination of pregnancy or prematuredelivery;
• Documented discussion with the treating team and the patient;
• Patient agrees.